Posted Jun 15, 2007 at 09:27AM by Ryan A. Listed in: Genetics Tags: Genome, DNA, Human Genome Project
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Human Genome Poject - Image 1We don't want to go into debate about this one but the Human Genome Project was never really completed. Back in 1995, it was considered "pragmatically complete" at 92% and the remaining 8% of DNA found in human cells were never really studied.

Now The Encyclopedia of DNA Elements (Encode) is trying to understand the so-called "letters of the genome". Prior to all these, the scientific community generally believes that the genome activity is focused on the 22,000 genes with known functions, making up around 3% of all our genes.

The remaining 97%, furthermore, are known as junk DNA because it is still unknown what functions they serve. The latest findings of Encode is currently challenging that belief. According to Dr. Tim Hubbard from the Wellcome Trust Sanger Institute,

We are now seeing the majority of the rest of the genome is active to some extent. The genome looks like it is far more of a network of RNA transcripts that are all collaborating together. Some go off and make proteins; [and] quite a few, although we know they are there, we really do not have a good understanding of what they do.


Hubbard, together with his team, focused on 1% of the human genome sequence, carrying out 80 different types of experiments that generated more than 600 million data points. The scientist mentioned that these data will be further combined with other findings.

The Human Genome Project and Encode, you see, are collaborative efforts between 80 organizations from around the world.


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   by mohaas05 (Unregistered) - 2007-06-15
 » yeah

i saw this today in the washington post



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